Lateral Flow Tests (LFTs), once a pandemic staple for detecting Covid-19, are now transforming into versatile diagnostic tools. From detecting strokes to monitoring vitamin levels, the technology is expanding its reach far beyond its original purpose.
Expanding Uses for Lateral Flow Tests
During the Covid-19 pandemic, LFTs became a common method for quickly identifying infections. As the pandemic fades, this technology continues to evolve. Boots UK has recently introduced finger-prick LFTs to measure vitamin D, iron, and cholesterol levels. They have also launched a test for influenza detection. Meanwhile, researchers are exploring the use of LFTs for early stroke detection, with studies now testing various sample types, including fingerprint sweat, river water, and even cat vomit.
LFTs work by detecting specific molecules without requiring costly lab equipment. The test involves a plastic cartridge containing antibodies designed to bind with target molecules. When the molecules are present, they trigger a visible line in the test window, indicating a positive result. The first commercial LFT, the Clearblue pregnancy test, launched in the late 1980s. However, until the Covid-19 pandemic, pregnancy testing remained the primary application of this technology. The global health crisis spurred rapid innovation and expansion in LFT usage.
A New Era of Diagnostics
According to Dr. Chris Hand, chair and co-founder of Abingdon Health, LFTs are now seen as a credible alternative to traditional lab testing. “People now see lateral flow as a serious alternative to lab testing,” he stated. “Testing on-site or at the point of care allows immediate action.”
The pandemic also led to a massive increase in LFT manufacturing, making these tests more accessible worldwide. As self-testing became a common practice, more people grew comfortable with the process and benefits of LFTs.
“The beauty of lateral flows is their simplicity,” said Gonzalo Ladreda, CEO of Upfront Diagnostics, a company working on developing LFTs for early stroke detection. “You place a sample, and a line means positive—no line means negative.”
Future Potential of Lateral Flow Tests
With their simplicity, affordability, and adaptability, LFTs are set to revolutionize diagnostics. Researchers and companies are actively exploring new applications, which could transform the way diseases and health conditions are detected and managed. As more advancements are made, LFTs could become an essential tool for everyday healthcare needs.
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